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Mov Disord off J Mov Disord Soc 35:1466–1471 [DOI] [PMC free article] [PubMed] [Google Scholar] Comi C et al (2014) Peripheral nervous system involvement in Parkinson’s disease: evidence and controversies

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In addition, there was limited efficacy, and a lacking of curative effects in the original cytoprotection implementation by prostaglandins given (pleiotropic) beneficial effects occurring mostly with application before injury induction [42]