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Studies revealed that in aged rhesus monkeys (20-26 years), Epithalon increased melatonin levels more than 3-fold compared to baseline, restoring circadian patterns characteristic of younger animals

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Even when ingested in normal amounts, copper and iron may become toxic in certain individuals with genetic predispositions that lead to hepatic overload - iron overload in hemochromatosis [11-17] or copper overload in Wilson disease [18-27]