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Here we describe that: (Schultheiss et al., 2019): GHRP-6 administration concomitant to Dox challenge prevented the onset of DCM/HF, (Riehle and Bauersachs, 2019), GHRP-6 significantly reduced animals’ morbidity and mortality, attenuated epithelial damages in a multi-organs spectrum, and inhibited Dox-related parenchymal fibrotic induration, (Hershberger et al., 2013), GHRP-6 triggered multiple defense mechanisms, involving oxidative stress reduction and activation of detoxifying enzymes, enhancement of prosurvival gene expression, and cardiomyocytes mitochondrial structural preservation

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[DOI] [PubMed] [Google Scholar] 25.Burwinkel B., Kreuder J., Schweitzer S., Vorgerd M., Gempel K., Gerbitz K.-D., Kilimann M.W