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Some people may notice mild digestive changes when starting a new supplement, and long-term use has been associated with a potential decrease in zinc levels in some individuals

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In the study examining depression, researchers saw improvements in the Hamilton Rating Scale for Depression—a 17-item rating scale for depression symptom severity—in patients taking sulforaphane following surgery for coronary artery bypass graft or percutaneous coronary intervention (Ghazizadeh-Hashemi et al., 2021)