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Darutigenol has been shown to possess anti-RA properties by effectively suppressing joint inflammation and inhibiting cartilage degradation through the IL-6/JAK1,3/STAT3 pathway
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5.2 Finely tuning GPX4 level in selectively targeted tissues or cells is of significance In addition to preventing lipid peroxidation and ferroptosis, GPX4 also fulfills other physiological functions, including modulating inflammation, immunity, autophagy and differentiation [15,23]
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