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Hormonal fluctuations, particularly during pregnancy or when taking oral contraceptives, can trigger melasma, a type of hyperpigmentation characterized by symmetrical brown patches typically appearing on the face

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In the oral cavity, a unique feature to be handled by the host defence is that continuously replaced bacteria may obtain a firm anchorage on the nonshedding tooth surface and will thereby remain in close contact with the soft tissues surrounding the tooth for a long time and evoke inflammation (1, 2)