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Although few studies have explored the effect of LIPUS on matrix remodeling in the final stage of recovery from skeletal muscle injury, some articles have proved that LIPUS can inhibit myocardial fibrosis in the rat model of myocardial injury, which has certain reference significance for the future study into LIPUS inhibiting fibrosis after skeletal muscle injury

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In 2014, researchers showed that knocking down the NNMT gene protected mice against diet induced obesity (the 2014 Nature paper reporting that nicotinamide N-methyltransferase knockdown protects against diet-induced obesity)