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JH reported receiving grants from Prati-Donaduzzi, travel support and personal fees from BioSynthesis Pharma Group, being a co-owner of a patent for fluorinated cannabidiol compounds (licensed to Phytecs), and having a patent pending for a cannabinoid-containing oral pharmaceutical composition outside the submitted work

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Upregulation of CHAC1 has been consistently observed in models of retinal damage, kidney and liver injury and heat shock–induced oxidative stress, often in tandem with ER stress (Ju et al., 2025