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Simultaneous determination of glycyl-L-histidyl-L-lysine and its metabolite, L-histidyl-L-lysine, in rat plasma by high-performance liquid chromatography with post-column derivatization

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in Cell Metabolism , increased NAD⁺ availability stimulates PGC-1α through SIRT1 activation, leading to enhanced mitochondrial function and improved metabolic flexibility (Cantó et al., Cell Metabolism )