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Results are mixed, with modest effects on social cognition and anxiety in some studies but inconsistent replication Cortistatin: Endogenous peptide with anxiolytic properties in animal models through somatostatin receptor activation
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After one-third of the study participants have been enrolled and completed follow-up, the DSMBs will review the data and make recommendations concerning continuation, modification or termination of the study due to unexpectedly large beneficial effects or serious side effects and can suggest extension of the trial should the primary outcomes occur less often than anticipated
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