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Human Data: Three Small Pilot Studies The complete published human evidence base for BPC-157 includes: A 2021 retrospective uncontrolled chart review of intra-articular knee injections in 16 patients, reporting subjective pain relief in 91.6% of BPC-157-only patients based on phone-survey self-report, with no control group and no standardized outcome instruments A 2024 pilot study giving 12 women with interstitial cystitis a single intravesical injection of BPC-157, reporting no adverse events A 2025 intravenous safety pilot in two healthy adults receiving escalating doses, reporting no measurable cardiac, hepatic, renal, thyroid, or glucose changes Total human subjects across all three studies remains under 30
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